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Disseminated Intravascular Coagulation

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Signs and Symptoms

Signs and symptoms of DIC depend upon the underlying condition and on the severity and the extent of DIC. Some examples include:

  • Fever
  • Low blood pressure
  • Blood and/or protein in the urine

Some signs and symptoms of DIC are associated with bleeding and/or inappropriate clotting.

Significant bleeding usually occurs from at least three different sites.

  • Blood in the stool or urine from internal bleeding
  • Headaches and other symptoms associated with bleeding in the brain
  • Bruising and the formation of small red dots on the skin (petechiae)
  • Bleeding at the site of wounds, surgical sites, intravenous (IV) needle or catheter sites
  • Mucosal bleeding – from the nose, gums, mouth, etc.

Blood Clotting
Symptoms depend on the location of blood clots and may include:

  • Symptoms associated with organ dysfunction caused by blood clots blocking blood flow and oxygen to organs such as the liver and kidney, leading to liver and kidney failure
  • Blackening of the skin caused by blockage from blood clots and poor blood flow to the skin
  • Chest pain, coughing up blood, and/or difficulty breathing caused by blood clots in the lungs
  • Chest pain and/or a heart attack caused by clotting in the heart
  • Headaches and other symptoms associated with a stroke, caused by clotting in the brain

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