ApoE Genotyping
Also known as: ApoE cardiac risk; ApoE 2 mutations; APOE4 genotype
Formal name: Apolipoprotein E genotyping
Related tests: Cardiac Risk Assessment; HDL Cholesterol; LDL Cholesterol; Lipid Profile; Triglycerides; Tau/Aß42
At a Glance
Why Get Tested?
Apo E genotyping is not widely used. The clinical usefulness of this test is still being researched. However, it may be used in two different conditions:
- For cardiovascular risk assessment, to help make treatment decisions for individuals with cardiovascular disease or to help confirm a diagnosis of Type III hyperlipoproteinemia (also known as familial dysbetalipoproteinemia)
- As an aid in the diagnosis of probable late onset Alzheimer's disease in a symptomatic adult
When to Get Tested?
- When your doctor suspects that you have an inherited component to your high cholesterol and triglyceride levels or if you have yellowish lesions called xanthomas on your skin
- When you have progressive symptoms of dementia and your doctor wants to determine the likelihood that this is due to Alzheimer’s disease
Sample Required?
A blood sample drawn from a vein in your arm
Test Preparation Needed?
None





