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HLA Testing

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Also known as: Tissue Typing; HLA Typing; Histocompatibility Testing; HLA Crossmatching; HLA Antibody Testing/Screening/Identification
Formal name: Human Leukocyte Antigen; HLA Oligotyping; HLA Sequence-based Typing
Related tests: Blood Typing; HLA-B27; HLA-A, B, C, DR and DQ

At a Glance

Why Get Tested?

To identify which human leukocyte antigen (HLA) genes and antigens a person has inherited, primarily to match up donors and recipients of organ and bone marrow transplants and to detect antibodies to HLA antigens that would cause transplants to be unsuccessful

When to Get Tested?

Most often, transplant recipients are tested when it is determined that they need an organ or bone marrow transplant, prior to seeking and selecting a suitable donor; potential donors are tested when they are being evaluated for compatibility with a specific recipient or are signing up with a national donor registry.

Sample Required?

A blood sample drawn from a vein in your arm; sometimes, for HLA typing, a swab from the inside of the cheek (buccal swab)

Test Preparation Needed?